產(chǎn)品基本信息
產(chǎn)品編號(hào)：T789500
產(chǎn)品名稱(chēng)：N-Trifluoroacetyl-N-methyl-deacetylcolchiceine
產(chǎn)品CAS：1217782-80-3
規(guī)格含量：1g
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
T789500
名稱(chēng):
N-Trifluoroacetyl-N-methyl-deacetylcolchiceine
別名:
2,2,2-Trifluoro-N-methyl-N-[(7S)-5,6,7,9-tetrahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide;
CAS號(hào):
1217782-80-3
分子式:
C??H??F?NO?
外觀:
Yellow Solid
分子量:
453.41
溶解度:
Chloromethane, Dichlormethane, DMSO, Methanol
類(lèi)別:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
參考文獻(xiàn)
Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
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