產(chǎn)品基本信息
產(chǎn)品編號：A602985
產(chǎn)品名稱：4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
產(chǎn)品CAS：956025-99-3
規(guī)格含量：100mg
產(chǎn)品價格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
A602985
名稱:
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
別名:
3-[(3-Bromophenyl)methyl]-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-BrB-PP1;
CAS號:
956025-99-3
分子式:
C??H??BrN?
狀態(tài)：
灰白色至淺褐色固體
熔點(diǎn)：
140-142°C
分子量:
360.25
儲存：
冰箱保存
溶解性:
Chloroform (Slightly), Methanol (Slightly)
類別:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
參考:
Eblen, S., et al.: J. Biol. Chem., 278, 14926 (2003), Lindsley, C., et al.: Bioorg. Med. Chem. Lett., 15, 761 (2005), Manning, B., et al.: Cell, 129, 1261 (2007), Heerding, D., et al.: J. Med. Chem., 51, 5663 (2008),
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