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產(chǎn)品基本信息

產(chǎn)品編號(hào)：C422245

產(chǎn)品名稱：4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-Chloro-3-(trifluorometh

產(chǎn)品CAS：

規(guī)格含量：2.5g

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	C422245
名稱:	4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate
別名:	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[[(4-Chloro-3-(trifluoromethyl)phenylamino)carbonyl]oxy]-2-fluorophenyl]-Urea
分子式:	C??H??Cl?F?N?O?
分子量:	570.24
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
參考文獻(xiàn)	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

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