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產(chǎn)品基本信息

產(chǎn)品編號：D446073

產(chǎn)品名稱：4,?4-?Difluoro-?N-?[(1S)?-?3-?hydroxy-?1-?phenylpropyl]?-cyclohexanecar

產(chǎn)品CAS：376348-77-5

規(guī)格含量：25mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標(biāo)準(zhǔn)品編號:	D446073
名稱:	4,?4-?Difluoro-?N-?[(1S)?-?3-?hydroxy-?1-?phenylpropyl]?-cyclohexanecarboxami?de
別名:	4,4-Difluoro-N-((1S)-3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide; UK 453465
CAS號:	376348-77-5
分子式:	C??H??F?NO?
外觀:	白色固體
分子量:	297.34
溶解性:	Dichloromethane
種類:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	4,?4-?Difluoro-?N-?[(1S)?-?3-?hydroxy-?1-?phenylpropyl]?-cyclohexanecarboxami?de is an intermediate in synthesizing Maraviroc-d6 (M193002), a potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral.
參考文獻	Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003); Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005); Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005)

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