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產(chǎn)品基本信息

產(chǎn)品編號：E589090

產(chǎn)品名稱：α-Epoxyabiraterone Acetate

產(chǎn)品CAS：

規(guī)格含量：50mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	E589090
名稱:	α-Epoxyabiraterone Acetate
別名:	(4S,6aR,6bS,8aS,8bR,9aR,10aS,10bR)-6a,8a-Dimethyl-8b-(pyridin-3-yl)-3,4,5,6,6a,6b,7,8,8a,8b,9a,10,10a,10b-tetradecahydro-1H-naphtho[2',1':4,5]indeno[1,2-b]oxiren-4-yl Acetate
分子式:	C??H??NO?
外觀:	白色至白色固體
熔點:	>190°C (dec.)
分子量:	407.55
儲存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
穩(wěn)定性:	Hygroscopic
種類:	Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
參考文獻(xiàn)	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

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