Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
4-(4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl)-1-(prop-1-en-2-yl)-1H-1,2,4-triazol-5(4H)-one is an intermediate in synthesizing rel-4-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-(prop-1-en-2-yl)-1H-1,2,4-triazol-5(4H)-one (T767490), which is an impurity of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazole (K186000). Also antifungal.
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