Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides; Semi-Synthetic;
應(yīng)用:
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-erythromycin 9-[2-(Triphenylmethyl)hydrazone] is an intermediate in the synthesis of 12-O-Methyl Clarithromycin which is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
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