Hygroscopic, -20?C Freezer, Under Inert Atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; Opiates; Natural Products;
應(yīng)用:
A metabolite of Naltrexone (N285750). Methylnaltrexone (MNTX; M320350), a selective μ-opioid receptor (MOR) antagonist, functions as a peripherally acting receptor antagonist in tissues of the gastrointestinal tract. When opiates activate μ-opioid receptors (MORs) they trigger signaling pathways that lead to tolerance and hyperalgesia. Methylnaltrexone (M320350) is positively charged and therefore does not cross the blood brain barier. Mice given morphine with methylnaltrexone experienced pain relief without degeloping tolerance.
危險(xiǎn)品:
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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