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產(chǎn)品基本信息

產(chǎn)品編號(hào)：T367005

產(chǎn)品名稱(chēng)：Thiomuscimol Biotin

產(chǎn)品CAS：

規(guī)格含量：2.5mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	T367005
名稱(chēng):	Thiomuscimol Biotin
別名:	Thiomuscimol-d-Biotin; Thiomuscimol-(3aS,?4S,?6aR)?-Hexahydro-?2-?oxo-?1H-?Thieno[3,?4-?d]?imidazole-?4-?pentanoic Acid, Thiomuscimol Meribin; Thiomuscimol Medebiotin; Thiomuscimol D(+)-Biotin
分子式:	C??H??N?O?S?
分子量:	356.46
類(lèi)別:	Research Tools; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Thiomuscimol (62020-54-6 #CAS) conjugated with Biotin (B389040 #CAS). This is a useful compound for research and organic synthesis. Biotin is a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue. On the other hand, Thiomuscimol has a photoaffinity label for the GABAA receptor. Thiomuscimol inhibits [3H]muscimol binding to brain GABAA receptors.
參考文獻(xiàn)	Lykkeberg, J., et al.: Acta Chem. Scand., B, 30, 781 (1976), Bureau, M.H., et al.: J. Neurochem., 61, 1479 (1993), N'Goka, V;., et al.: J. Med. Chem., 34, 2547 (1991); du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942); Traub, et al.: Nature, 178, 649 (1956); Siegel, H., et al.: Experienta, 37, 789 (1981); Vesely, D.L., Science, 216, 1329 (1982); Hugues, M., et al.: Biochemistry, 31, 12 (1992);

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