N-{2-Chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methylisoxazol-3-yl)urea; AV 951; KRN 951; Kil 8951; N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea;
CAS號(hào):
475108-18-0
分子式:
C??H?? ClN?O?
外觀:
Pale Beige to Light Brown Solid
熔點(diǎn):
>202°C (dec.)
分子量:
454.86
儲(chǔ)存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly, Heated)
類別:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Tivozanib is known as an oral VEGF receptor tyrosine kinase inhibitor, exhibiting antitumor effects towards renal cell carcinoma.. Tivozanib suppresses angiogenesis by selectively inhibiting against vascular endothelial growth factor. Potent VEGFR inhibitor.
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