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產品基本信息
產品編號：A779985
產品名稱：AS 2444697
產品CAS：1287665-60-4
規(guī)格含量：10mg
產品價格：面議
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產品詳細介紹
標準品編號:
A779985
名稱:
AS 2444697
別名:
N-[3-(Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide Hydrochloride; N-[3-Carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide Hydrochloride;
CAS號:
1287665-60-4
分子式:
C??H??N?O?•HCl
分子量:
396.403646
類別:
Standards; Enzyme Activators and Inhibitors;
應用:
AS 2444697 is a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor. It suppressed the progression of chronic renal failure via anti-inflammatory action in nephrectomized rats.
文獻
Kondo, M., et al.: Naunyn Schmiedebergs Arch. Pharmacol., 387, 909 (2014);
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