產品基本信息
產品編號：C984525
產品名稱：[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
產品CAS：66845-32-7
規(guī)格含量：100mg
產品價格：面議
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產品詳細介紹
標準品編號:
C984525
名稱:
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
別名:
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN,κN']diiodoplatinum; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; (trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-Cyclohexane-1,2-diamine)diiodoplatinum; Diiodo(trans-l-1,2-cyclohexanediamine)platinum; NSC 290127; [SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N')diiodoplatinum; USP Oxiplatin Related Compound F;
CAS號:
66845-32-7
分子式:
C?H??I?N?Pt
外觀:
淡黃色固體
熔點:
>300°C
分子量:
563.08
儲存:
-20°C Freezer
溶解度:
DMSO (Slightly)
類別:
Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN')diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
參考文獻
Kidani, Y. et al.: Biomed. Pharmacther., 43, 261 (1989); Noji, M. et al.: J. Med. Chem., 24, 508 (1981); Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),
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