Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid can be used to study cytochrome P 450 isoforms involved in the bioactivation of diclofenac to reactive p-benzoquinone imines (4).
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