Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
6’-Ketopravastatin Lactone is a metabolite of Pravastatin Sodium via enzymically dehydrogenation, which exhibits β-hydroxydehydrogenase activity; Also, it is an intermediate used in the synthesis of Pravastatin 6-Ketone Sodium Salt (P702050), which is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of HMG-CoA reductase. It can be used as a drug to for lowering cholesterol and preventing cardiovascular disease.
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