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產(chǎn)品基本信息

產(chǎn)品編號(hào)：N388600

產(chǎn)品名稱：Necrosulfonamide

產(chǎn)品CAS：432531-71-0

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	N388600
名稱:	Necrosulfonamide
別名:	N-[4-[[(3-Methoxypyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylamide;
CAS號(hào):	432531-71-0
分子式:	C??H??N?O?S?
外觀:	Yellow Solid
熔點(diǎn):	200-204°C(dec.)
分子量:	461.47
儲(chǔ)存:	Amber Vial, 冰箱, Under Inert Atmosphere
溶解度:	DMSO, Methanol
種類:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.
參考文獻(xiàn)	Sun, L. et al.: Cell, 148, 213 (2012);

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