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產(chǎn)品基本信息

產(chǎn)品編號：S143753

產(chǎn)品名稱：Saxagliptin Hydrochloride

產(chǎn)品CAS：709031-78-7

規(guī)格含量：100mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	S143753
名稱:	Saxagliptin Hydrochloride
別名:	(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile Hydrochloride;
CAS號:	709031-78-7
參考CAS號:	Free Base: 361442-04-8
分子式:	C??H??N?O? • (HCl)
外觀:	白色固體
熔點(diǎn):	>219°C
分子量:	315.413646
儲存:	-20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
類別:	Standards; Enzyme Activators and Inhibitors;
應(yīng)用:	Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
參考文獻(xiàn)	Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),

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