產(chǎn)品基本信息
產(chǎn)品編號：T787025
產(chǎn)品名稱：N-Trifluoroacetyl Deacetylcolchicine
產(chǎn)品CAS：26195-65-3
規(guī)格含量：500mg
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
T787025
名稱:
N-Trifluoroacetyl Deacetylcolchicine
別名:
2,2,2-Trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-Deacetyl-N-(trifluoroacetyl)colchicine; NSC 305987;
CAS號:
26195-65-3
分子式:
C??H??F?NO?
外觀:
Faintly Yellow Crystalline Powder
分子量:
453.41
儲存:
冰箱
溶解度:
Chloromethane, Dichlormethane, DMSO, Methanol
類別:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
參考文獻
Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
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