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產(chǎn)品基本信息
產(chǎn)品編號：C124800
產(chǎn)品名稱：CAL-101
產(chǎn)品CAS：870281-82-6
規(guī)格含量：50mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
C124800
名稱:
CAL-101
別名:
5-Fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)propyl]-4(3H)-quinazolinone; CAL 101; Delalisib; GS 1101; Idelalisib; N6-[(S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl]adenine; Zydelig;
CAS號:
870281-82-6
分子式:
C??H??FN?O
外觀:
Pale Brown Solid
熔點(diǎn):
250-252ºC
分子量:
415.42
儲存:
冰箱保存, under inert atmosphere
溶解度:
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Very Slightly, Heated)
類別:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.
參考文獻(xiàn)
Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);
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