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產(chǎn)品基本信息

產(chǎn)品編號(hào)：D232060

產(chǎn)品名稱：3-Deoxy-3-acetylabiraterone-3-ene

產(chǎn)品CAS：

規(guī)格含量：50mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	D232060
名稱:	3-Deoxy-3-acetylabiraterone-3-ene
別名:	1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethanone
分子式:	C??H??NO
外觀:	白色至淡黃色固體
熔點(diǎn):	>120°C (dec.)
分子量:	373.53
儲(chǔ)存:	-20Â°C Freezer, Under inert atmosphere
溶解性:	Chloroform (Slightly), Methanol (Slightly, Heated)
種類:	Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	3-Deoxy-3-acetylabiraterone-3-ene is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
參考文獻(xiàn)	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

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