鹽酸右雷佐生（ICRF-187，ADR-529），≥99％
Product Name： Dexrazoxane HCl (ICRF-187, ADR-529)
CAS號(hào):149003-01-0
分子式:C11H16N4O4·HCl
分子量:304.73
貯存： 儲(chǔ)存溫度-20°C
可溶性：
DMSO 61 mg/mL
Water 61 mg/mL
Ethanol <1 mg/mL
生化和生理學(xué)機(jī)理：
Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, thus reduce the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs. From Wikipedia.
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