司骨化醇，≥99％
Product Name： Secalciferol
CAS號:55721-11-4
分子式:C27H44O3
分子量:416.64
介紹： (24R)-24,25-Dihydroxyvitamin D3
貯存： 儲存溫度-20°C
可溶性： DMSO Methanol Chloroform
生化和生理學(xué)機(jī)理：
Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid. Secalciferol is a vitamin D3 metabolite which is involved in bone ossification. In addition, it is known that Secalciferol mediates calcium and phosphorus homeostasis. Also Secalciferol inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. Alternate studies indicate that Secalciferol can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Furthermore, Secalciferol can increase cell proliferation in resting zone (RC) chondrocytes and inhibits matrix enzymes by possibly inhibiting the degradation of the matrix.
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