2,5-二叔丁基對(duì)苯二酚(DBHQ),98%
ProductName:2,5-Di-tert-butylhydroquinone(DBHQ)
別名:DTBHQ;2,5-二叔丁基氫醌;2,5-二特丁基對(duì)苯二酚;2,5-二第三丁基對(duì)苯二酚;2,5-二(1,1-二甲基乙基)-1,4-苯二醇
CAS號(hào):88-58-4
分子式:[(CH3)3C]2C6H2-1,4-(OH)2
分子量:222.32
介紹:2,5-Di-tert-butylhydroquinone(DBHQ)hasbeenshowntobeaselectiveandpotentinhibitorofSERCA(endoplasmicreticulumCa2+-ATPase)whichisshowntocauseinductionofCa2+releasefromagonist-insensitiveandagonist-sensitiveintracellularstores.Inisolatedrathepatocytestudies,DBHQwasreportedtoinducearapidincreaseincytosolicCa2+concentrationwithoutlossofothermicrosomalenzymeactivity,alteringmembranepermeability,ormodificationofmicrosomalproteinthiols.
用途:AninducerofCa2+
熔點(diǎn):215°C
沸點(diǎn):216°C
特定比重:1.012
敏感性:對(duì)光和空氣敏感
可溶性:Solubleinacetone,benzene,aqueousalkali,DMSO(25mg/mlwarm),and100%ethanol.
生化和生理學(xué)機(jī)理:阻斷人體β細(xì)胞的鈣依賴性胰島素信號(hào)
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