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產(chǎn)品基本信息

產(chǎn)品編號(hào)：C291155

產(chǎn)品名稱：Cetirizine Propanediol Ester Dihydrochloride(Mixture of regioisomers)

產(chǎn)品CAS：

規(guī)格含量：500mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	C291155
名稱:	Cetirizine Propanediol Ester Dihydrochloride(Mixture of regioisomers)
別名:	2-Hydroxypropyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate Dihydrochloride;
分子式:	C??H??Cl?N?O?
外觀:	白色至Pale Pink Solid
熔點(diǎn):	133 - 136Â°C
分子量:	519.89
儲(chǔ)存:	Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:	Methanol (Slightly), Water (Slightly)
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Cetirizine Propanediol Ester Dihydrochloride, is the Cetirizine (C281100) impurity, which is nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
參考文獻(xiàn)	De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

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