產(chǎn)品基本信息
產(chǎn)品編號：C291700
產(chǎn)品名稱：CH5132799
產(chǎn)品CAS：1007207-67-1
規(guī)格含量：5mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
C291700
名稱:
CH5132799
別名:
5-[6,7-Dihydro-7-(methylsulfonyl)-2-(4-morpholinyl)-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-pyrimidinamine; [5-[7-Methylsulfonyl-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrimidin-2-yl]amine
CAS號:
1007207-67-1
分子式:
C??H??N?O?S
分子量:
377.42
類別:
Research Tools;
應(yīng)用:
CH5132799 is a selective class I phosphoinositide 3-kinase (PI3K) inhibitor that targets human cancers harboring oncogenic PIK3CA mutations. CH5132799 also showed potent antiproliferative and antitumor activity.
參考文獻(xiàn)
Kondoh, O., et al.: BIO Clinica, 28, 488 (2013); Tanaka, H., et al.: Clin. Cancer Res., 17, 3272 (2011); Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 21, 1767 (2011)
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