Palbociclib, ≥99%
Product Name： Palbociclib
CAS號:571190-30-2
分子式:C24H29N7O2
分子量:447.53
貯存： 儲存溫度-20°C
可溶性： DMSO
生化和生理學機理：
Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib is a highly specific inhibitor of cyclindependent kinase 4 (Cdk4) (IC50, 0.011 μmol/L) and Cdk6 (IC50, 0.016 μmol/L), having no activity against a panel of 36 additional protein kinases.
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